NANOCOMPOSITE POLYMER COATINGS WITH PROLONGED DELIVERANCE OF MEDICINAL COMPONENTS (VANCOMYCINUM, FOSFOMYCINUM, POLYMIXINUM B AND C)

Purpose

Deposition of nanocomposite polymer coatings with prolonged deliverance of medicinal components (vancomycinum, fosfomycinum, polymixinum B and C) on the surfaces of the implants allows decrease the risks of postoperative complications caused by the intrahospital infections. During the coating process the substrate does not undergo thermal or any other energy impacts, making it possible to form the coatings on all the types of substrates (metal, polymer, paper, etc) without changes of their physico-chemical characteristics.

Advantages:

  • The coating can be applied on all the types of materials (metal, polymer, etc.), and the end-product without changes of its physico-mechanical characteristics;
  • After coating the item is immediately ready for use;
  • An opportunity to form composite coatings containing chemotherapeutic agents based on a wide nomenclature of polymer materials: polylactide, polyurethane, polyoxymethylene, polytetrafluoroethylene, polymethylmethacrylate, and others. The choice of a polymer matrix can provide a particular speed of deposition of a metal or an antibacterial component into the biological environment in the process of gradual degradation of the polymer base.
  • An opportunity to process a significant amount of items, that decreases the prime cost of this kind of processing;
  • This method does not require the use of aqueous media, being a one-stage;
  • It allows forming coatings on the surfaces of any (conductive and nonconductive) finished products;
  • The processes of precipitation and protonation are carried out directly in the gas phase and on the substrate during the interaction of the dispersing products with each other.

Readiness degree:

  • The project of technical specifications for antibacterial coating
  • Prototypes of coatings
  • Patents of the Republic of Belarus for the invention

 

Offer: transfer of technology, know-how, technical support during technology’s introduction

 


ALEXANDER ROGACHEV,
DIRECTOR OF PHYSICO-CHEMICAL RESEARCH AND DEVELOPMENT INSTITUTE,
CORRESPONDING MEMBER OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF BELARUS,
DOCTOR OF CHEMICAL SCIENCES, PROFESSOR,
tel. (+375 232) 50 38 03, fax (+375 232) 51 00 77,
e-mail: rogachevav@mail.ru,
http://nis.gsu.by


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